Collagen is the most
abundant protein in the human body, making up around 30% of the total protein content.
It is a central structural component of skin, bones, joints, tendons, muscles, gums, and teeth, as well as other tissues and organ structures. Collagen is found exclusively in animal and human tissue. This protein
gives tissue strength, stability, and elasticity. In its natural form, collagen is a large and complex molecule that forms insoluble, stable fibers that cannot be easily broken down by the
human digestive system. Therefore, natural collagen cannot be directly digested or absorbed.

Hydrolyzed collagen, also known as collagen peptides, is produced by enzymatic hydrolysis, which breaks down native collagen into smaller components. These peptides are water-soluble, more easily digestible, and available to the body.

You can easily stir our collagen powder into drinks and food. Our recommended dosage: 1-2 tablespoons a day.

Ideally first thing in the morning on an empty stomach or before you go to bed.

The taste is neutral / typical for the species

What is Hydrolyzed Collagen (bioactive collagen peptides)?

Collagen is exclusively an animal protein. It is found in animal tissues (native collagen) and is a very long and complex molecule that cannot be used as a nutrient because our digestive system cannot digest it and therefore cannot utilize it [1][2].

For collagen to become digestible and assimilable, two processes are necessary:

Gelatinization: Unwinding of the triple helix collagen molecule. This process, which yields gelatin, usually occurs through chemical processes (bases or strong acids) [3]. However, for the production of Jennifer Frey collagen, only a physical treatment (heat) is applied.

Hydrolysis: Breaking down long collagen polypeptide chains (gelatin) into peptides (short chains) by enzymes, as found in the human digestive system [1][4].

[1]: Hydrolyzed Collagen—Sources and Applications. MDPI. DOI: 10.3390/molecules24224031.

[2]: Fratzl, P. (2008). Collagen: Structure and Mechanics, an Introduction. In: Fratzl, P. (Eds.) Collagen. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-73906-9_1

[3]: Gelatin properties, production and molecular structure. University of Bayreuth. https://daten.didaktikchemie.uni-bayreuth.de/umat/gelatine/Gelatine.pdf

[4]: The effect of various collagen hydrolysates on the metabolism of human articular cartilage. Justus Liebig University Giessen. https://jlupub.ub.uni-giessen.de/bitstreams/b1574d5b-c8d7-4925-8a27-8fef789b00cf/download

Collagen in the Human Body

Collagen is the most abundant and widespread protein in our body. This extremely resistant and flexible molecule forms the structure of all tissues, provides protection, and enables us to stand and move [1].

It makes up about 70% of the dry weight of cartilage, 20% of bones, 85% of tendons, 70% of ligaments, 75% of skin, and 6% of muscles. It is also the main component of connective tissue, which envelops and protects all our internal, vital organs [1][2].

[1]: Fratzl, P. (2008). Collagen: Structure and Mechanics, an Introduction. In: Fratzl, P. (Ed.) Collagen. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-73906-9_1

[2]: Effect of oral collagen peptides on whole-body skin quality. Georg Thieme Verlag KG Stuttgart · New York. DOI: 10.1055/a-1047-2822

Scientific Studies on Hydrolyzed Collagen

Hydrolyzed collagen is the subject of numerous scientific investigations related to nutrition, joint health, skin, muscles, and other physiological processes.

Below you will find a selection of relevant scientific publications from various fields of application.

Note: The following studies are for informational purposes only and, according to current EU law, do not constitute healing claims or efficacy claims in connection with our products.

General

“Revisión de los efectos beneficiosos del colágeno hidrolizado” – Nutrición Hospitalaria, 2015, 32(1): 62–66

"Impacts of Collagen Intake and Its Biological Significance" – J Nutr Food Sci, 2016, 6:504

"Functional Collagen Peptides: Importance for Nutrition" – Nutrients, May 15, 2019;11(5)

"Positive Effects of Hydrolyzed Collagen: Overview of Current Developments" – Biomed J Sci & Tech Res, 2017, 1(2)

Bioavailability

“Digestibility of Hydrolyzed Collagen during Passage through a Dynamic Gastric and Small Intestinal Model (TIM-1)” – TNO Food and Nutrition Research Report. June 24, 2002

Joints

"A Randomized Controlled Trial on the Efficacy and Safety of a Food Ingredient, Hydrolyzed Collagen, to Improve Joint Comfort" – International Journal of Food Sciences and Nutrition, 2009, 60(S2): 99–113

"24-week study on the use of hydrolyzed collagen in sport-related joint pain" – Current Medical Research and Opinion, 2008, 24(5): 1485–1498

"Effects of Hydrolyzed Collagen in Osteochondral Lesions of the Knee and Ankle: A Case Series" – Int J Case Rep Images, 2017;8(6):364–369

"Double-Blind, Placebo-Controlled Study of Collagen Peptides in Osteoarthritis" – J Sci Food Agric., 2015;95(4):702–707

"The Role of Hydrolyzed Collagen in Bone and Joint Diseases" – Seminars in Arthritis and Rheumatism, 2000;30(2):87–89

"Efficacy of Enzymatically Hydrolyzed Collagen vs. Glucosamine Sulfate in Knee Osteoarthritis" – Int Orthop., 2011;35:341–348

Tendons and Ligaments

“Oral Collagen Peptide Supplementation with Training Improves Function in Achilles Tendinopathy” – Nutrients, 2019 Jan 2;11(1)

Bones

“Biological Effect of Hydrolyzed Collagen on Bone Metabolism” – Crit Rev Food Sci Nutr, 2017, 57(9): 1922–1937

“Specific Collagen Peptides Improve Bone Mineral Density in Postmenopausal Women” – Nutrients, 2018, 10(97)

“Collagen as an Adjunctive Therapy for Osteoporosis and Osteoarthritis” – Rev Bras Geriatr Gerontol, 2016, 19: 153–164

“Serum after Collagen Intake Modulates Bone Cell Activity” – Nutrients, 2019, 11(1249)

Skin

“Oral Collagen Peptide Supplementation: Ex Vivo and Clinical Evidence on Skin Moisture” – J Cosmetic Dermatology, 2015

“Hydrolyzed Collagen with Vitamins Improves Skin Elasticity” – Clin Pharmacol Biopharm, 2015, 4:142

“Hydrolyzed Collagen and Skin Health: Overview of Clinical Studies” – The Open Nutraceuticals Journal, 2015, 8: 29–42

“Collagen Peptides and Dermal Fibroblasts at Different Body Sites” – Cell Biol Int., 2018 Jan;42(1):95–104

“Optimal Dosage of Hydrolyzed Collagen Against UVB Damage” – Biosci Biotechnol Biochem., 2016;80(2):356–359

“Bioactive Collagen Hydrolysates Improve Wound Healing in Pressure Ulcers” – Scientific Reports, 2018, Article 11403

Muscles

“Collagen Peptides + Strength Training: Muscle Strength in Premenopausal Women” – Nutrients, 2019 Apr 20;11(4)

“12 Weeks of Training + Collagen Peptides: Influence on Muscle Proteome” – Nutrients, May 14, 2019;11(5)

“Hydrolyzed Collagen in Fibromyalgia and Temporomandibular Joint Pain” – Cranio, 18(2): 135–141

“Collagen Peptide Supplementation Improves Muscle Strength in Older Men” – Br J Nutr, 2015, 114:1237–1245