How long until collagen works? What the research says
One of the most common questions about collagen as a dietary supplement is: How long does it take to see results? In this article, we provide an overview of the current state of scientific research.
Important note: There are currently no approved health claims for collagen as an ingredient under EU Regulation No. 1924/2006 (HCVO). The following information provides an overview of the current state of scientific research and does not constitute a promise of healing.
What happens after taking collagen?
Collagen is a protein found in various tissues in the body. After oral intake, hydrolyzed collagen (collagen peptides) is broken down into amino acids and short peptide chains in the digestive tract and absorbed through the intestines. Scientific studies have shown that specific collagen peptides are detectable in blood plasma after ingestion (Iwai et al., 2005).
What do studies say about study periods?
4 weeks
Some studies use periods of 4 weeks. During this time, initial changes in measured parameters can be observed, with results varying depending on the study and measurement method.
8 weeks
Proksch et al. (2014) conducted their investigations over 8 weeks. The authors reported statistically significant differences in measured skin parameters between the collagen and placebo groups. An 8-week period is common in collagen research.
12 weeks and longer
Some studies, such as Clark et al. (2008) with a 24-week period, use longer observation periods. Longer study durations allow for the observation of changes over an extended period.
Important factors in research
The timeframes used in studies vary depending on:
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Type of collagen – Type I, II, or III; hydrolyzed or as tripeptide
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Dosage – the amounts used in studies vary widely (2.5g to 15g daily)
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Parameter investigated – different studies measure different endpoints
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Study design – quality and independence of the studies vary
Classification
Collagen research is in an active stage of development. Many studies have limited participant numbers and are sometimes co-financed by manufacturers. EFSA has not yet approved any health claims for collagen. Further independent long-term studies are needed to make reliable statements.
Conclusion
Scientific studies on collagen peptides often use periods of 8 to 24 weeks. Results vary depending on the study design, collagen type used, and parameter measured. As a dietary supplement, collagen can be part of a balanced diet.
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This article is for informational purposes only and does not constitute medical advice. Dietary supplements are not a substitute for a balanced and varied diet and a healthy lifestyle.
