Spermidine – what's behind the longevity cell substance?

What is Spermidine?

Spermidine is a naturally occurring polyamine – an organic compound found in almost all living cells. It is produced by the body itself and is also contained in various foods.

Spermidine belongs to the group of polyamines, which also includes putrescine and spermine. These compounds play an important role in fundamental cellular processes.

Note: No health claims for spermidine are permitted in the EU under the Health Claims Regulation (EC) No. 1924/2006. This article serves exclusively for general information about spermidine as a naturally occurring substance.

Where does Spermidine naturally occur?

The richest food sources

Spermidine is found in many foods – particularly concentrated in:

• Wheat germ: ~243 mg/kg – one of the richest sources overall
• Soybeans (aged): ~207 mg/kg
• Cheddar cheese (aged): ~199 mg/kg
• Mushrooms (button mushrooms): ~89 mg/kg
• Peas: ~65 mg/kg
• Broccoli: ~31 mg/kg

Spermidine in the body

The body produces spermidine itself – via polyamine metabolism. However, endogenous production decreases with age. At the same time, dietary intake decreases for many people over their lifetime.

Autophagy – the cell cleansing process

What is Autophagy?

Autophagy (Greek: "self-eating") is a natural cell cleansing process in which cells break down and recycle damaged or no longer needed components. The term became known worldwide through the Nobel Prize in Physiology or Medicine 2016 (Yoshinori Ohsumi).

Spermidine is one of the most intensively researched natural substances in connection with autophagy. Research in this area is active and constantly growing – however, approved EU health claims are not yet available.

Spermidine in science

Spermidine is one of the most studied polyamines in longevity research. Research groups worldwide – including the University of Graz and Charité Berlin – are intensively engaged with spermidine. The scientific data situation is growing, but approved health claims according to HCVO are not yet available.

Our product

Spermidine Tablets – 6.0 mg per daily dose – 180 Tablets

• ✔ 6.0 mg spermidine per daily dose – high-dose
• ✔ 180 tablets – large supply
• ✔ 100% vegan
• ✔ Laboratory-tested quality
• ✔ Made in Germany – according to German quality standards

What to look for when buying?

• Dosage: Spermidine content per daily dose transparently indicated (mg)
• Source: Wheat germ extract as a natural source of spermidine
• Purity: Laboratory-tested quality without unnecessary fillers
• Vegan: Plant-based tablets without animal additives
• Manufacturing standard: Made in Germany

Application

Please refer to the product label for the recommended intake. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Keep out of reach of small children.

Conclusion

Spermidine is a naturally occurring polyamine found in almost all cells and concentrated in foods such as wheat germ (~243 mg/kg), soybeans, and aged cheese. Research on spermidine and autophagy is active and international – approved EU health claims are not yet available. Our Spermidine 6.0 mg – 180 Tablets offers laboratory-tested, vegan quality, Made in Germany.

Frequently Asked Questions (FAQ)

What is Spermidine?

Spermidine is a naturally occurring polyamine found in almost all living cells. It is produced by the body itself and is concentrated in foods such as wheat germ (~243 mg/kg), soybeans (~207 mg/kg), and aged cheese (~199 mg/kg).

Which foods contain the most spermidine?

The richest natural sources of spermidine are: wheat germ (~243 mg/kg), aged soybeans (~207 mg/kg), aged cheddar (~199 mg/kg), button mushrooms (~89 mg/kg), peas (~65 mg/kg), and broccoli (~31 mg/kg).

What is autophagy?

Autophagy (Greek: "self-eating") is a natural cell cleansing process in which cells break down and recycle damaged or no longer needed components. The process became known worldwide through the Nobel Prize in Physiology or Medicine 2016 (Yoshinori Ohsumi).

Are there approved health claims for spermidine?

No. For spermidine, no health claims are permitted in the EU under the Health Claims Regulation (EC) No. 1924/2006. The product is offered as a food supplement.

How much spermidine is in a daily dose?

The CollMeCell Spermidine product contains 6.0 mg of spermidine per daily dose – laboratory-tested, 100% vegan, Made in Germany.

Does the body's own spermidine production decrease with age?

Yes. The body's own production of spermidine and other polyamines decreases with age. At the same time, dietary intake decreases for many people. This is an active field of research in longevity science.

Is spermidine vegan?

Spermidine itself is a naturally occurring organic compound. The CollMeCell Spermidine product is 100% vegan – without animal additives, laboratory-tested, Made in Germany.