Longevity Supplements: What's Behind NMN, Spermidine & Co.?

Longevity is no longer a niche topic. In Germany, Austria, and Switzerland, interest in active ingredients that are supposed to support cellular processes is growing rapidly. Terms like buy NMN, NAD+ Booster experiences, or spermidine effects generate thousands of search queries on Google every month.

What is NAD+ – and why is research interested in it?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every body cell and involved in numerous metabolic processes. Scientific studies show that NAD+ levels in the body decrease with age.

NMN (nicotinamide mononucleotide) is a precursor to NAD+ and is being investigated in human studies. Initial results – such as a study by Keio University (2020) – indicate good tolerability. Definitive statements on efficacy in humans are currently not possible. You can find more information on NMN in our detailed article NMN Food Supplements – Effects, Application & What Science Says.

Note: Food supplements are not medicines. They are not intended to treat, cure, or prevent diseases.

Spermidine: Autophagy and Cell Cleaning

Spermidine is a naturally occurring polyamine found in foods such as wheat germ, soybeans, and aged cheese. In basic research, it is being investigated in connection with autophagy – the cellular self-cleaning process.

An observational study by the University of Innsbruck (Madeo et al., Nature Medicine, 2018) showed correlations between spermidine intake and certain health parameters. Causal conclusions cannot be drawn from this.

If you want to supplement spermidine specifically, you can find our Spermidine Tablets 6.0 mg (180 pcs.) – vegan, lab-tested, Made in Germany. Spermidine is also included as a component of our INTENS GLOW RITUAL Collagen pure.

  • Declared quantity per daily dose (mg spermidine)
  • Origin and purity of the wheat germ extract
  • Manufactured according to GMP standards, ideally in Germany

Resveratrol: Polyphenol from Grapes

Resveratrol is a secondary plant compound from grape skins and red wine. It has been extensively studied in cell and animal experiments; its transferability to humans has not yet been conclusively clarified. Those taking blood-thinning medication should seek medical advice before taking it.

Urolithin A: Novel Food from the Gut

Urolithin A is not formed directly in food, but is produced by gut bacteria from ellagic acid (e.g., from pomegranate). It is approved as a Novel Food in the EU (Implementing Regulation (EU) 2022/48). A study in Nature Metabolism (2019) showed effects on mitochondrial markers in muscle tissue.

Further Longevity-Relevant Supplements from Our Range

In addition to NMN and spermidine, there are other active ingredients that are receiving attention in longevity research and are available from us:

What to Look for When Buying

  • Transparent declaration: Active ingredient quantity per daily dose clearly stated
  • GMP manufacturing: Ideally in Germany or the EU
  • Third-party lab analyses: Independent purity certificates for heavy metals and pesticides
  • No unauthorized health claims: Reputable providers adhere to the HCVO
  • Medical consultation: Especially for pre-existing conditions or medication use

Conclusion

Longevity research is developing rapidly. Active ingredients such as NMN, spermidine, resveratrol, and urolithin A are being actively investigated – definitive statements on efficacy in humans are still pending for many substances. Those who want to try longevity supplements should focus on quality, transparency, and realistic expectations.

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